Zhang Shihong(Zhang SH), Wu Lichang(Wu LC), Zhao Zhonglin(Zhao ZL), et al, . Improved synthesis of clodronateJ. Chinese Journal of Modern Applied Pharmacy, 2001, (1): 48-49.
Citation:
Zhang Shihong(Zhang SH), Wu Lichang(Wu LC), Zhao Zhonglin(Zhao ZL), et al, . Improved synthesis of clodronateJ. Chinese Journal of Modern Applied Pharmacy, 2001, (1): 48-49.
Zhang Shihong(Zhang SH), Wu Lichang(Wu LC), Zhao Zhonglin(Zhao ZL), et al, . Improved synthesis of clodronateJ. Chinese Journal of Modern Applied Pharmacy, 2001, (1): 48-49.
Citation:
Zhang Shihong(Zhang SH), Wu Lichang(Wu LC), Zhao Zhonglin(Zhao ZL), et al, . Improved synthesis of clodronateJ. Chinese Journal of Modern Applied Pharmacy, 2001, (1): 48-49.
OBJECTIVE:To study the synthesis of clodronate.METHODS:Clodronate was synthesized by steps of condensation,chloration,pyrolysis and salifying from dibromomethane and triisopropyl phosphite.RESULTS:The chemical structure of synthetic product was confirmed
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