Lu Jinrong(Lu JR), Ma Ying(Ma Y). Synthesis of gemfibrozil[J]. Chinese Journal of Modern Applied Pharmacy, 2000, (2): 124-125.
    Citation: Lu Jinrong(Lu JR), Ma Ying(Ma Y). Synthesis of gemfibrozil[J]. Chinese Journal of Modern Applied Pharmacy, 2000, (2): 124-125.

    Synthesis of gemfibrozil

    • OBJECTIVE:To synthesize gemfibrozil and optimize the process.METHOD:Gemfibrozil was synthesized from 3-(2,5-xylyloxyl) propyl chloride which was reacted with sodium isobutyrate first and then react with n butyllithium.3-(2,5-xylyloxyl) propyl chloride wa
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