Literature Analysis of Adverse Drug Reaction Induced by Angiotensin Converting Enzyme Inhibitor

OBJECTIVE To discuss the characteristics and generally clinical patterns of adverse drug reaction(ADR) induced by angiotensin converting enzyme inhibitor(ACEI). METHODS The 838 ADR cases induced by ACEI which were reported in internal medical journals published from Jan 1989 to Apr 2010 were collected by retrieving China hospital digital library and analyzed statistically. RESULTS The ADR cases induced by ACEI are much more in the elder. The ADRs involved multiple systems, expecially the respiratory system (581 cases, 69.33%). The prognosis of ADR is generally good. CONCLUSION The cause of ADR induced by ACEI is varied. Correct understanding and omnibearing monitoring can effectively reduce or even avoid the occurrence of ADR induced by ACEI.