Pharmacoeconomic Evaluation of Surgical Weight Loss Surgery and Drug Therapy for Type 2 Diabetes Mellitus Accompanied with Obesity Patients

OBJECTIVE To analyze the economy of laparoscopic subtractive surgery and traditional drug therapy in the treatment of type 2 diabetes mellitus (T2DM) accompanied with obesity.METHODS A total of 76 patients with T2DM accompanied with obesity from June 2014 to May 2016 in Nanjing Drum Tower Hospital were enrolled in this study (Group A:received laparoscopic subtracted gastric bypass surgery; Group B:received drug therapy). Decision Tree was used to analyze the cost-effective of the two groups.RESULTS The expected cost of group A and group B were 47 353 and 3 838 yuan in 24 weeks respectively, the cost-effectiveness ratios were 485.1 and 40.8 respectively; the expected cost of group A and group B were 47 438 and 6 588 yuan in 48 weeks respectively, the cost-effectiveness ratios were 486 and 70.CONCLUSION From the results of cost-effectiveness analysis, drug treatment of T2DM accompanied with obesity is more economical than surgical methods.