Abstract: OBJECTIVE　To investigate the effect of Ficus Carica polysaccharide on the levels of interleukin-1a produced by peritoneal macrophages, lymphocyte proliferation, interleukin-2 and its receptor in immunosuppressive mice. METHODS　Immunodeficiency mice induced by injecting cyclophosphamide were divided into high and low dosage groups of Ficus Carica polysaccharide solution (with the dosage of 400, 100 mg·kg-1 respectively), xianggu duotang pill group (100 mg·kg-1), iso-volume physiological saline group and blank control group, with 6 mice in each group. Administration was carried out with the same time of model estahlisbment for successive 7 days. The interleukin-1a produced by peritoneal macrophages, lymphocyte proliferation, formation and activity of IL-2 in spleen cells and the level of SIL-2R in mice were measured. RESULTS　Ficus Carica polysaccharide can promote the secretion of IL-1α in peritoneal macrophages and IL-2 in spleen cell, and reduce the level of serum SIL-2R in the immunosuppressive mice. CONCLUSION　Ficus Carica polysaccharide exhibits better effect on im-proving immunocopetence.