甘草酸及其脂质配位体的理化性质与抗肝损害作用的比较
Study on the physico-chemicals and liver protective effect of glycyrrhizinphosphatidylcho line complex
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摘要: 目的:增加甘草酸的保肝作用。方法:在隋性溶剂中将甘草酸与磷脂酰胆碱形成配位体口服。结果:甘草酸形成脂质配位体后从水溶性变为脂溶性,理化性质(红外、紫外光谱、高效液相等)无明显改变,抗肝损作用明显增加。结论:口服甘草酸脂质配位体的抗肝损作用明显优于甘草酸。Abstract: OBJECTIVE:in order fo raise the liver protecve activity of oral glycyrrhizin.METHOD:The lipophilic complexe of glycyrrhizin was preparated via glycyhrhizim and phospholipids in the presence of inert solvent.RESULTS:The increasing liposolubility of glycyrr
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