磺胺的噻二嗪硫酮衍生物的合成及抑菌活性研究

Synthesis and Antimicrobial Activities of Some New Tetrhydro-2H-1,3,5-Thione Dervatives of Sulfanilamide

摘要: 利用药物化学骈合原理设计并合成了一系列新的3,5-二取代1,3,5-噻二嗪-2-硫酮类化合物,其结构被红外光谱与紫外光谱及元素分析所证实,抑菌活性试验显示了良好的抑菌活性.

Abstract: A number of new 3-substituted-5-para aminobenfene sulphonyl-tetrahydro- 2H1,3,5-thiadiazine-2-thiones had been synthesized as antibacterial and antifungal compound. The structure of these compounds have been elucidated by UV, IR and elementary analysis. T