利妥昔单抗致视物模糊、视力下降不良反应1例并文献复习

    Rituximab-induced Blurred Vision and Decreased Vision: A Case Report and Literature Review

    • 摘要:
      目的 分析1例48岁女性因自身免疫性郎飞结病使用利妥昔单抗治疗后,出现视力下降、视物模糊的罕见不良反应。
      方法 通过回顾该患者的诊疗过程,结合文献对利妥昔单抗致视力下降、视物模糊的不良反应进行探讨。
      结果 通过对该患者诊疗过程的分析及诺氏不良反应评估量表评估,考虑该患者出现视力下降、视物模糊的症状与利妥昔单抗相关。
      结论 利妥昔单抗在临床中广泛应用,其不良反应的类型和表现形式呈现多样化,需要引起临床医师的高度关注,并通过加强监测与管理,进一步提升用药安全性。

       

      Abstract:
      OBJECTIVE To analyze a rare adverse reaction of rituximab manifesting as decreased vision and blurred vision in a 48-year-old female patient with autoimmune nodopathy.
      METHODS The adverse reactions of rituximab-related decreased vision and blurred vision were investigated by reviewing the patient’s clinical diagnosis and treatment course, combined with a systematic literature review.
      RESULTS Based on the analysis of the patient’s clinical management and evaluation using the Naranjo’s assessment scale for adverse drug reactions, the patient’s symptoms of decreased vision and blurred vision were determined to be associated with rituximab administration.
      CONCLUSION Rituximab is widely utilized in clinical practice, yet its adverse reactions exhibit diverse types and manifestations. This necessitates heightened vigilance among clinicians, who should enhance monitoring and management strategies to further improve the safety of rituximab therapy.

       

    /

    返回文章
    返回