Abstract: With the continuous development of big data and artificial intelligence technology, the internet hospital, as an emerging medical model, has been continuously constructed and improved. This development has also brought the relationship and interaction between precision medicine and personalized pharmaceutical care closer, propelling medical services towards a higher level. Medical services are developing towards a higher level. However, it is still challenging to provide patients with personalized precision dosage medical services correctly and efficiently. This article addresses the current status of precision personalized medication service model, analyzes the harm of the lack of accurate dosing and the shortcomings of dose distribution methods in the existing oral solid preparations. The construction of a new 3D printing technology for precise dosing of oral solid preparations is proposed. In the context of precision medicine, a new model and way of pharmaceutical care based on 3D precise dose distribution combined with the internet is explored, and the innovative development of personalized precision medicine for patients is realized, so as to provide accurate and effective pharmaceutical care for patients.