1例惠普尔养障体致肺部感染的药物治疗分析

    Pharmacotherapy Analysis of One Case of Pulmonary Infection Caused by Tropheryma Whipplei

    • 摘要:
      目的 提高对肺部感染惠普尔养障体抗感染药物治疗的认识。
      方法 回顾性分析1例惠普尔养障体引起免疫力正常患者肺肿物的临床资料,通过查阅指南和近3年相关文献报道,分析及总结惠普尔养障体致肺部感染的抗感染药物治疗方案。
      结果 患者使用头孢曲松联合复方磺胺甲噁唑抗感染治疗后病情好转,继续复方磺胺甲噁唑序贯治疗,随访结果显示肺肿物明显缩小,治疗有效。
      结论 惠普尔养障体致免疫正常患者肺肿物较罕见,应及时明确病原菌,尽早使用以头孢曲松、复方磺胺甲噁唑为基础的单药或者联合治疗的抗感染方案。

       

      Abstract:
      OBJECTIVE  To enhance understanding of antimicrobial therapy for pulmonary infections caused by Tropheryma whipplei.
      METHODS  The clinical data of one case of lung mass caused by Tropheryma whipplei in an immunocompetent patient were retrospectively analyzed, and the anti-infective drug treatment plan for lung infection caused by Tropheryma whipplei was analyzed and summarized by reviewing the guidelines and the relevant literature reports in the past three years.
      RESULTS After receiving anti-infective treatment with ceftriaxone combined with cotrimoxazole, the patient's condition improved. The patient continued with sequential therapy using cotrimoxazole. Follow-up results showed a significant reduction in the lung mass, indicating that the treatment was effective.
      CONCLUSION Lung mass in immunocompetent patients due to Tropheryma whipplei are rare, and the pathogen should be promptly identified and an anti-infective regimen based on ceftriaxone and cotrimoxazole, either as a single agent or in combination, should be used at the earliest possible time.

       

    /

    返回文章
    返回