Abstract: OBJECTIVE To analysis the risks of ganciclovir using in children, and to formulate security policy.METHODS The failure mode and effect analysis method were used to search for the failure modes of ganciclovir in pediatric drug therapy by literature searching, questionnaire survey, field investigation and other steps.RESULTS Five failure modes of ganciclovir in pediatric drug therapy were obtained through the risk priority score, and precautionary strategies were established for these failure modes.CONCLUSION There are still many risks of ganciclovir in all aspects of pediatric clinical use. In China, there are few laws on children's rational use of drugs.