Research Progress on Anti-influenza Effective Components of Isatidis Radix
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Graphical Abstract
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Abstract
Isatidis Radix is the dry root of Isatis indigotica Fort. of the Brassicaceae plant. It is a representative traditional Chinese medicine for clearing away heat and detoxifying, cooling blood and relieving pharynx. It is commonly used in the prevention and treatment of respiratory viral diseases. At present, more than one hundred chemical components in Isatidis Radix have been identified, and the molecular diversity is very rich. However, there is a lack of systematic evaluation and discussion on the pharmacological activities of these compounds, such as anti-influenza active ingredients. This article discusses the isolation and identification of Isatidis Radix active ingredients, then studies the modern pharmacological research progress of Isatidis Radix antiviral active ingredients against influenza. This review provides new ideas and references for secondary development and application of Chinese medicinal herbs.
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