Measurement of Particle Size Distribution of Ginseng Powder by Laser Light Scattering Method

OBJECTIVE To establish a laser light scattering method for the determination of particle size distribution for ginseng powder. METHODS The Malvern Mastersizer 3000E and AERO M dry autosampler were used for determination. The conditions of determination were as follows: gap height was 1.5 mm, dispersing pressure was 3.5 bar, feed rate was 60%, the refraction rate was 1.52, the measurement time of background and sample was 30 s, the absorption of 0.01, and the obscuration was 0.5%-5%. RESULTS RSD of Dv(10), Dv(50) and Dv(90) were all <4% in the repeated messurement results of 5 batches of ginseng powder, which were all in line with the requirements of China Pharmacopeia 2015 edition. CONCLUSION The determination method of laser light scattering method is stable and reliable, and it’s suitable for the particle size control of ginseng powder.