Influence of the Medication Administration Sequence of Docetaxel and Epirubicin on the Therapeutic Effect During Chemotherapy for Breast Cancer

OBJECTIVE To analysis the effectiveness of chemotherapy that the medication administration sequence of anthracycline and taxanes in neoadjuvant therapy for breast cancer. METHODS Medical records with different medication administration sequence of epirubicin and docetaxel in 2010-2014 were analyzed. They were divided into control group(epirubicin first, 34 cases) and control group(docetaxel first, 58 cases). The short-term?curative?effects were evaluated after 3 courses of treatment. RESULTS The short-term effective rate of control group was 61.76%, while the survival benefit was 85.29%. The short-term effective rate of observation group was 74.13%, while the survival benefit was 91.37%. CONCLUSION It is more effective to use taxanes before anthracycline in neoadjuvant therapy for breast cancer.