CHEN Xuan, TONG Yeling, REN Zeming, YANG Feng, DAI Guanhai. Effect of Myricanone on Cell Apoptosis and Cell Cycle in Human Lung Adenocarcinoma A549 Cells[J]. Chinese Journal of Modern Applied Pharmacy, 2015, 32(1): 14-17.
    Citation: CHEN Xuan, TONG Yeling, REN Zeming, YANG Feng, DAI Guanhai. Effect of Myricanone on Cell Apoptosis and Cell Cycle in Human Lung Adenocarcinoma A549 Cells[J]. Chinese Journal of Modern Applied Pharmacy, 2015, 32(1): 14-17.

    Effect of Myricanone on Cell Apoptosis and Cell Cycle in Human Lung Adenocarcinoma A549 Cells

    • OBJECTIVE To detect the effect of myricanone on cell apoptosis and cell cycle in human lung adenocarcinoma A549 cells. METHODS The early cell apoptosis rate and cell cycle percentage of each group were detected by flow cytomytry. RESULTS Myricanone induced early cell apoptosis of A549 cells in a dose-dependent manner, as well as increased the percentage of A549 cells blocked in G0/G1 stage. CONCLUSION Myricanone could significantly increase the cell apoptosis rate of A549 cells and could block cell cycle of A549 cells in G0/G1 stage.
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