Establishment of A Safety Test Method of Elemene Injection

OBJECTIVE To establish standards for safety tests of elemene injection. METHODS Study on pyrogen, bacterial endotoxins, haemolysis and blood cell agglutination, undue toxicity, depressor substance, systemic anaphylaxis, vascular stimulation and writhing tests by Ch.P(2010) Vol Ⅰ, Ⅱ, the guiding principles of drag and experimental methods in pharmacology. RESULTS Established the standard of pyrogen, haemolysis and blood cell agglutination, undue toxicity, systemic anaphylaxis, vascular stimulation and writhing tests. While bacterial endotoxins and depressor substance test standard not be established. CONCLUSION Provided experimental method for elemene injection.