Comparison of Levamlodipine Besylate Tablets from Five Manufacturers in Content, Related Substances and Dissolution

OBJECTIVE To provide references for clinical medication by evaluating the quality of 5 kinds of Levamlodipine Besylate tablets. METHODS Examining the content, related substances and dissolution of Levamlodipine Besylate tablets from 5 manufacturers, and comparing with Norvasc. RESULTS Among 5 kinds of Levamlodipine Besylate tablets, there was 1 kind of tablets failed, because the impurity was higher than the limit; 3 kinds of tablets were hardly equivalent to Norvasc; and only one kind of tablet was closest to the Norvasc in terms of content, related substances and dissolution. CONCLUSION There are significant qualitative differences among the domestic generic Levamlodipine Besylate tablets.