Etiological Investigation and Drug Sensitivity Analysis of Infectious Diseases in Emergency Observation Ward

OBJECTIVE To analyse etiological distribution and drug sensitivity of commonly used antimicrobial agents in emergency observation ward, providing a basis for the application of antibacterial drugs reasonably and infection control in the clinic. METHODS Retrospectively analysised the positive rate and pathogenic bacteria distribution and the sensitive rate of main pathogenic bacteria to commonly used antimicrobial agents of the specimens of The First People’s Hospital of Hangzhou emergency observation ward patients from July 2009 to June 2012. RESULTS There were 430 strains isolated during 3 years in emergency observation ward. Mainly for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, coagulase negative staphylococcus, Klebsiella pneumoniae and Acinetobacter, Baumanii the relevance ratio sums to 70%. E.coli was the main pathogenic bacteria, the sensitive rate of which to ceftazidime, carbapenems, piperacillin/tazobactam, cefoperazone/ shubatan was more than 75%. The sensitive rate of Pseudomonas aeruginosa to ceftazidime, cefepime, imipenem, piperacillin/tazobactam, cefoperazone/sulbactam, gentamicin, amikacin was more than 75%. The sensitive rate of Klebsiella pneumonia was more than 75% only to carbapenems, amikacin. The sensitive rate of baumanii was more than 75% only to carbapenems, cefoperazone/shubatan. The sensitive rate of Staphylococcus aureus and coagulase negative staphylococcus was more than 75% only to glycopeptide antibiotics and cotrimoxazole. The positive vate of extended-spectrum beta- lactamases(ESBLs)-producing Escherichia coil was 50.72%, which of Klebsiella pneumonia was 33.33%. The drug resistance rate of ESBLs producing bacterias was lower obviously than that of the bacteriaw which dodn’t produce ESBLs. CONCLUSION There are differences about the pathogenic bacteria distribution and drug resistance between emergency observation ward and both the community infection and hospital infection. The drug resistance rates are high to the main pathogenic bacteria and shows multidrug resistance. The sensitive rate of carbapenems, cefoperazone/shubatan and glycopeptide antibiotics are high to gram positive and gram negative bacteria. Emergency physicians should use antibiotics reasonably for treatment referring to susceptibility results.