Clinical Observation on 15 Colorectal Cancer Patients in Blood Hypercolktive State Treated with Aidi Injection

OBJECTIVE To explore the intervention effect of Aidi injection on blood hypercolktive state of 15 patients with advanced colorectal cancer by means of testing plasma D-dimer’s levels. METHODS Thirty cases with colorectal cancer with abnormal D-dimer values were randomly divided into control group and treatment group, 15 cases in each group, and treated with chemotherapy or Aidi injection combining chemotherapy separately. Their plasma D-dimer concentrations were measured by immunoturbidimetric assay before and after treatment. RESULTS D-dimer concentrations of 10 cases in control group rose, the others reduced. No significant difference was found before and after treatment. D-dimer concentrations of 3 cases in treatment group rose, the others reduced. A significant difference of mean was found before and after treatment(P<0.01). The rate of decline and the deviation values of D-dimer were statistically significant difference between two groups(P<0.05 and P<0.01). CONCLUSION Aidi injection can ameliorate D-dimer concentrations of large intestine patients in blood hypercolktive state. Chemotherapy does not influence the plasma D-dimer concentrations of patients with colorectal cancer.