Study on Polygalae Radix and Alcohol Extract by FTIR

OBJECTIVE To establish and compare the differences of Polygalae Radix medicines’ FTIP produced in different areas, and explain the infrared spectroscopy characteristics of these Polygalae Radix medicines. METHODS Common peak ratio analysis, variant peak ratio analysis, and cluster analysis of Polygalae Radix medicines and alcohol soluble extractives’ FTIP spectrum were done. RESULTS In 3 300, 2 930, 2 850, 1710, 1 650, 1 510, 1 450, 1 260, 1 060, 600 cm^-1, FTIR spectra from ten different areas had ten common peaks, and with Shanxi as the control group received an average of original group’ common peak ratio was 85.7%. The average of alcohol soluble extract group’s co-peak rate was 79.0%. By cluster analysis, Shanxi Polygalae Radix were the same to the most Polygalae Radix, they were in the same subclass. CONCLUSION Shanxi Polygalae Radix is representative, and infrared spectroscopy analysis provides another method for Polygalae Radix quality control.