Anti-inflammatory Effects of Decoctions of Different Varieties Clematidis Radix et Rhizoma by External Use on Hemorrhoid and Adjuvant-induced Arthritis Rat Model

OBJECTIVE To summarize the external function of Clematidis Radix et Rhizoma through the experimental study of external use. METHODS Observed the effects of three varieties of Clematidis Radix et Rhizoma, water decoction for external use on rats model of hemorrhoid and rats adjuvant-induced arthritis model. RESULTS Water decoction of Clematis chinensis Osbeck, C. hexapetala Pall, C. manshurica Rupr. could improve rats model of hemorrhoid symptoms of perianal ulcers, accelerated wound healing, promote healing and reduce the perianal swelling, reduced arthritis in rats model of plantar foot swelling, improve joint swelling and motor impairment symptoms, reduced serum inflammatory factors in IL-1β, TNF-α level. CONCLUSION External use of Clematidis Radix et Rhizoma can repair pathological tissue, speed up the uleer area healing with anti-inflammatory fuction.