Relationship of Roxithromycin Crystal Types, Dissolution Rates and Dissolution

OBJECTIVE To study the crystal types of roxithromycin, and the relationship of roxithromycin crystal types and its dissolution rate and dissolution. METHODS X-ray powder diffraction and infrared spectroscopy were used in the analysis of crystal types. The dissolutive apparatus was used with 100 r·min^-1. RESULTS The result showed that three crystals of roxithromycin were different crystal types, and the dissolution rates and dissolutions of different crystal types had some differences. CONCLUSION The study provids a scientific basis for the effectiveness of roxithromycin.