Preparation of Amygdalin Gel

OBJECTIVE To screen amygdalin gel matrix to determine the preparation process. METHODS Using transdermal diffusion test instrument in vitro, the content of amygdalin in the received solution was determined by HPLC. Steady-state penetration rate was served as investigation indexes by orthogonal test. RESULTS Matrix dosage included 1%carbomer, 15% glycerin, 10%propylene glycol, 0.5% triethanolamine. CONCLUSION The preparation is simple, and the transdermal effect is good.