Compatibility of Propofol Emulsion

OBJECTIVE To investigate the compatibility of propofol emulsion combined with lidocaine injection and/or dexamethasone injection. METHODS Centrifugal spectrophotometry, Sudan test, conductivity measuring, pH and laser particle size analysis were used to observe the stability of propofol(group A), propofol and lidocaine mixed by 9∶1(group B), propofol and lidocaine mixed by 4∶1(group C), propofol and lidocaine and dexamethasone mixed by 3∶1∶1(group D) within 6 hours under room temperature. RESULTS The Ke of group B, C, D were significantly increased compared with group A, (P<0.05). Each group showed no stratification and color change. The pH of group B was decreased compared with group A at each time(P<0.05). The conductivity value of group A