Effect of Qilianbaizhu Granule on Chronic Ulcerative Colitis

OBJECTIVE To observe the effect of Qilianbaizhu granule on chronic ulcerative colitis. METHODS Ulcerative colitis model was established by dextran sodium sulfate(DSS). The effect of Qilianbaizhu granule with 3 different dosages on chronic ulcerative colitis was observed. RESULTS Compared with the model group, Qilianbaizhu granule with high, middle dose group significantly improved symptoms in different degree, DAI of high dose group significantly decreased (P<0.05); the animal's overall situation and colitis pathological condition compared with the model group improved　significantly. CONCLUSION Qilianbaizhu granule has obvious curative effect on chronic ulcerative colitis induced by DSS.