Quantitative Determination of Patchouli Alcohol in Huoxiang Zhengqi Dripping Pill By GC

OBJECTIVE To determine the content of Patchouli alcohol in Huoxiang Zhengqi Dripping Pill by GC. METHODS The GC separation was performed on capillary gas chromatographic column; FID flame ionization detector; carrier gas is nitrogen; temperature setting: sampling input temperature 280 ℃; column temperature 165 ℃,temperature programming process; detector temperature 280 ℃; split ratio: 5∶1; sample size: 1 μL. RESULTS In the GC experiments of precision, reproducibility and stability, the samples could be separated entirely. For patchouli alcohol, the linear range was 0.030 0-0.961 0 μg(r=0.999 9), the average recoveries were 101.1% with RSD=1.45% and it was stable in 24 h. CONCLUSION The method was sensitive, simple, accurate and reproducible, can be used to control the quality of Huoxiang Zhengqi Dripping Pill.