Investigation and Analysis on the Hypoglycemic Treatment Protocols among Patients with Type 2 Diabetes in County Hospital

OBJECTIVE To investigate the usage of hypoglycemic drugs among the type 2 diabetic patients in county hospital. METHODS From July 2010 to June 2011, 747 cases accompanied type 2 diabetes mellitus that were discharged with a better health condition were retrospectively analyzed and divided into A, B and C group according to departments of endocrinology, other medical and surgery. We investigated the use of drug, hypoglycemic treatment protocols, glucose levels and glycosylated hemoglobin in each group before and after admission, and compared the rationality of the hypoglycemic treatment protocols, usage of drugs that could influence blood glucose levels, patient compliance and blood glucose control with each group. RESULTS Usage rate of premixed insulin and analogue ± oral antidiabetic agents increased from 24% to 46.4% in group A (P<0.005). Usage of the strengthening scheme of rapid-acting insulin + long-acting insulin ± oral antidiabetic agents increased significantly in each group (P<0.005). Usage of long-acting insulin ± oral antidiabetic agents highly increased in group A and B (P<0.005), but obviously decreased with the scheme of oral antidiabetic agents (P<0.01, P<0.05). Noncompliance of hypoglycemic treatment decreased significantly in group A and group B (P<0.005). The irrational drug-usage rate of hypoglycemic treatment protocols in group A, B and C was 15.1%, 20.7%, 25.4%, respectively. And it was significantly higher in group C than that in group A (P<0.05). The rate of fasting blood glucose which was under controlled satisfactory level in group A, B and C was 32.7%, 31.4%, 20.1%, respectively. Only 20 percents of patients’ postprandial blood glucose was ideal or passable in each group. CONCLUSION The irrational drug use rate was high in hypoglycemic treatment protocols in type 2 diabetic patients. And the blood glucose was also poorly controlled by non-diabetes specialists in county hospital, especially the surgeons.