Mechanisms of Arsenic Trioxide Used in Cancers Therapy

Arsenic trioxide(As₂O₃，ATO) is one of the most effective therapeutic agents for patient with acute promyelocytic leukemia(APL), common but irreplaceable. Depending on its potential values, it has also been developed for treatment of other forms of tumors (e.g. liver and lungs cancer). Although As₂O₃