Study and Application of Polyphosphazene Immunoadjuvant

Polyphosphazene adjuvants is an emerging type of vaccine immunoadjuvants, which is based on apolyphosphazene backbone. It has many advantages than other adjuvants especially in both immune irritancy and drug delivery performance. This paper deals with some specific aspects of Polyphosphazene adjuvants, such as structural properties, synthetic strategy, systematization, mechanism of action, degradation property of polyphosphazene as vaccine immunoadjuvants and preparation of polymer microspheres. The advantage and characteristic of polyphosphazene as vaccine immunoadjuvants have also been elaborated in this research. Ultimately, the developing prospects in this field are forecasted.