Effect of Intensive Antihypertensive Treatment on Prognosis in Patients with Hypertensive Cerebral Hemorrhage

OBJECTIVE To explore the efficacy and safety of intensive antihypertensive treatment in patients with acute hypertensive cerebral hemorrhage. METHODS All of 106 patients were divided randomly into two groups, the intensive treatment group(55 cases) and the control group(51 cases). The intensive treatment group were aimed to lower the systemic blood pressure(SBP) no more than 140 mmHg within 6 hours and maintained 24 hours after the onset of the hemorrhage if the SBP was higher than 140-150 mmHg. The BP-lowing of the control group was according to the AHA guidelines of the previous version. the size of the hematoma after 24 hours, the neurologic impairment on the 14th day as well as the efficacy of the treatment were compared. RESULTS The effective rate of the intensive treatment group and the control group was 87.2% and 60.8%, respectively, and the difference was statistically significant. The difference relating to the improvement of the neurologic impairment was also statistically significant. CONCLUSION Intensive antihypertensive treatment can significantly improve the prognosis of the patients with hypertensive hemorrhage.