Study on the Process of Extraction for Shurening Oral Liquid

OBJECTIVE To optimize the extraction and purification process of Shurening oral liquid by orthogonal design. METHODS The content of puerarin of Shurening oral liquid in water decotion and alcohol deposit fluid were detected by HPLC. The content of puerarin and dry extract rate were used as index; the effects of water volume, boiling time, extraction times and alcohol concentration on process of precipitation were also evaluated by orthogonal design. RESULTS The optimun water extraction process was as follows: water as extracting solvent, three times of extracting, 1.5 h for each time, 10 times volume of solvent to the decoction piedes; the optimal alcohol concentration for precipitation process was 65%. CONCLUSION The experimental results provide the basis for the process of extraction for Shurening oral liquid.