Clinical Observation on Treatment of Primary Nocturnal Enuresis with Xingpiyang’er Particles Combined with Psychological Behavior Therapy in Children

OBJECTIVE To observe the clinical efficacy and the recurrence rate of combination Xingpiyang’er particles and psychological behavior therapy for treating the primary nocturnal enuresis (PNE) in children. METHODS If the parents and children consented to accept the treatment for 2 months and to keep on follow-up, the children diagnosed as primary noctur- nal enuresis were randomized into two groups: 70 children were in physio-psychological treatment group alone; 87 children were in combined treatment group who were treated with combination Xingpiyang’er particles orally and psychology behavior therapy. If the parents and children did not accept treatment, they were enrolled into the control group and were followed-up. Then, the curative effects of the two groups were compared statistically after the 2 months treatment and compared again 3 months later. RESULTS The total effective rate of the combined group was 72.09%, and the physio-psychological treatment group were 46.37%, there was significant difference(P<0.05); the recurrence rate in combined group was 12.79% which was significantly lower than the physio-psychological treatment group (26.47%, P<0.05). CONCLUSION The combination of Xingpiyang’er particles and psychology behavior therapy might have better curative effect and lower relapse rate than that the single usage, no obvious adverse reaction is observed. It is easy to be accepted by children and more suitable for widespread use to treat PNE.