Effect of Pregabalin on Nerve Block during the Treatment of Postherpetic Neuralgia

OBJECTIVE To observe the effect of pregabalin on nerve block during the treatment of postherpetic neuralgia. METHODS All of 40 postherpetic neuralgia patients were divided randomly into two groups, the control group(A) and gabapentin group(B). All patients were performed with nerve block, and the patients in group B received oral gabapentin. Visual analog scale (VAS) and sleep quality score (QS) were evaluated and adverse reactions were recorded. RESULTS VAS and QS in two groups decreased significantly after treatment, but VAS and QS of group B decreased more significantly than those of group A. There was no difference in adverse reactions between two groups. CONCLUSION The effect of pregabalin on nerve block during the treatment of postherpetic neuralgia is synergistic.