Study on HPLC Fingerprints of the Antidiabetic-active Fraction of Schisandrae Chinensis Fructus

OBJECTIVE To study the HPLC fingerprints of the antidiabetic-active fraction of Schisandrae Chinensis Fructus for better quality control. METHODS Ten samples were analysed to establish the standard fingerprint of the effective parts of Schisandrae Chinensis Fructus by HPLC. The chromatographic conditions were: Dikma-C₁₈(250 mm×4.6 mm, 5 μm) column at the temperature of 40 ℃, a gradient mobile phase of methanol-water with a flow rate of 1 mL·min-1, the detection wavelength was set at 250 nm. RESULTS A standard HPLC fingerprint of the antidiabetic-active fraction of Schisandrae Chinensis Fructus was established with 9 indicated common peaks. CONCLUSION The established fingerprint is reliable and sensitive which could be used in the quality evaluation and control process of Schisandrae Chinensis Fructus products.