The Effect of Developing “the Intelligent Prescription Screening System about Non-antimicrobial Agents’ Dosage and Dosing Interval”

OBJECTIVE To develop “the intelligent prescription screening system about the non-antimicrobial agents’ dosage and dosing interval” in order to decrease adverse drug events and increase therapeutic efficacy. METHODS Base on the information system of the hospital to realize the connection between the non-antimicrobial agents’ dosage and dosing interval with patients’ ages, weights, body surface areas and renal functions. RESULTS Pick out one day’s data randomly, including 1 382 prescriptions of the non-antimicrobial agents in hospitalized patients, the “system” examined and provided 438 warnings. There were 172 warnings of overdosage each time and moderate dosing interval, 90 warnings of overdosage each time and inadequate dosing interval, 61 warnings of moderate dosage each time and inadequate dosing interval, 47 warnings of moderate dosage each time and excessive dosing interval, 36 warnings of inadequate dosage each time and moderate or inadequate dosing interval in adults with normal renal functions. There were 32 warnings of overdosage and excessive dosing interval in drugs that should be adjusted according to patients’ ages and renal functions. CONCLUSION This kind of connection is practical. When prescriptions which violate the rules of dose and (or) dosing interval are present, they can be found out by the “system”, but its effect on the clinical is to be proved.