Chemical Constituents of the Root of Uncaria macrophylla

OBJECTIVE To study the chemical constituents of the root of Uncaria macrophylla Wall.. METHODS The plant was extracted by MeOH, then separated and repeatedly purified by methods of chromatography. Their structures were elucidated by IR, MS and NMR. RESULTS Six compounds were obtained and identified as rhynchophylline(1), isorhynchophylline(2), ursolic acid(3), b-sitosterol(4), taraxerol(5), myricadoil(6). CONCLUSION Chemical constituents of the root of Uncaria macrophylla were reported for the first time. These results would be benefit to the further investigation of this plant.