Effect of Bisoprolol on Myocardial Energy Expenditure(MEE) in Older Patients with Heart Failure(HF) and Chronic Fibrillation Atrial

OBJECTIVE To observe the effect of bisoprolol on myocardial energy expenditure (MEE) in older patients with heart failure (HF) and chronic fibrillation atrial. METHODS Forty-eight patients with atrial fibrillation were randomly divided into two groups: the observations were added with bisoprolol and the others were added with digoxin. The whole case were lasted for 12 months. To evaluate the relationship between MEE, LEVF、LVFS, Tei with patients. RESULTS LA of patients were not changed in 2 groups before and after treatment (P>0.05). To impove on heart function in 2 groups after treatment. RWT, LVMI, LVM, Tei index, cESS, MEE/sys, MEE/min, NT-proBNP were significantly higher in controls (P<0.01). CONCLUSION Bisoprolol can improve the left ventricle structural remodeling and heart function and reduce myocardial energy expenditure.