Study on Preparing Process Technology of Amomum Villosum Volatile Oil Dropping Pills

OBJECTIVE To study on the process technology of Amomum villosum volatile oil dropping pills. METHODS Orthogonal test was applied to select the optimum extraction parameters including percentage of the base, internal diameter of dropper, proportion of base to volatile oil, and cooling temperature. The optimal process technology was confirmed by the content of bornyl acetate which was determined by GC, weight difference, dissolution time and exterior of Amomum villosum volatile oil dropping pills. RESULTS The optimized process was as follows: the ratio of PEG4000 to PEG6000 was 1∶1, internal diameter of dropper was 2.0 mm, proportion of base to volatile oil was 2∶1 and cooling temperature was 0-5 ℃. CONCLUSION Amomum villosum volatile oil dropping pills which were produced by the optimal process technology were rich in bornyl acetate, and their weight difference, dissolution time as well as exterior met the requirements of Chinese Pharmacopoeia (2005 Edition).