Application of Fluorescence Spectrometry Determination Based on Charge-Transfer Reaction in Pharmaceutical Analysis

OBJECTIVE Introduce application of fluorescence spectrometry determination based on charge-transfer reaction in pharmaceutical analysis. METHODS Retrieve, classify and arrange documentations of China and abroad. RESULTS Charge-transfer complex can strongly enhance the fluorescence spectra, which also can remove the interference from urium and serum in pharmaceutical analysis in vivo by synchronous fluorimetry and derivate-synchronous fluorimetry. CONCLUSION The proposed method is simple, accurate, sensitive and low determination limit, so it appears to good application foreground in pharmaceutical analysis especially in trace analysis and pharmaceutical analysis in vivo.