Study on HPD-100 Macroporous Resin Regeneration Method

OBJECTIVE Look for a more simple method to improve service efficiency in the use of macroporous resin on purification of Chinese traditional medicine. METHODS Take atmospheric reflux by ethanol,to deal with HPD-100 macroporous resin after gardenia yellow pigment refining treatment. Through HPLC and colorimetry to compare appearance, adsorption and desorption etc with traditional acid-base method, desorption properties. And study the best treatment method under normal pressure of time and repetitive to test the stability of reflux. RESULTS Two ways to deal with after the macroporous resin is similar to the performance of basic, but atmospheric reflux less use of solvents, simple operation and safety. By experiment, regeneration of normal pressure to 5 hours for the most appropriate，and have good repeat stability. CONCLUSION That do not involve the ion exchange HPD-100 macroporous resin regeneration, atmospheric reflux can instead acid-base method to improve efficiency in the use of macroporous resin.