Study on Release Rate of Huangyangning Sustained-Release Capsules

OBJECTIVE To investigate the release rate of Huangyangning sustained-release capsules in vitro. METHODS Acidic dye spectrophotometry was used, with the release medium of 0.05 mol·L-1 sodium dihydrogen phosphate buffer solutions. The rotation speed was 100 r·min-1. RESULTS The average recovery was 98.5% (RSD=3.39%). The average cumulative releases for the three samples at 1 h, 4 h and 8 h were 23.10%, 57.39% and 85.86%, respectively. CONCLUSION The sustained-release capsules showed a favourable release property. The assay method of release rate in this paper could be used as quality control method.