Study on the Technology of Isolation and Purification of Gross Aalkaloid in Rhizoma Corydalis with Macropopous Adsorbing Resin

OBJECTIVE To explore the purification method of gross alkaloid in Rhizoma Corydalis with macropopous adsorbing resin.METHODS The extracting yield of the gross alkaloid were taken as index to select the macroporous resin.RESULTS Optium conditions for isolation and purification were indentified, I.e. D-101 type macropopous adsorbing resin,adsorbing rate was 0.5 BV·h-1,water volume for removing impurities was 6 BV,concentration of the ethanol was 80%,and volume of ethanol was 6 BV.CONCLUSION The method is simple and feasible,with good separating effect which can meet industrial requirements.