Preparation and Quality Control of Compound Ornidazole Hollow Type Suppository

OBJECTIVE To prepare and establish quality control for the compound ornidazole hollow type suppository.METHODSThe compound ornidazole hollow type suppository was prepared with mixable fatty acid glyceride as basic;The contents of ornidazole and levofloxacin were determined by equivalent absorption dual-wavelength method;The tests of hygienic, stimulation and stability were carried out. RESULTSThe average recovery of ornidazole and levofloxacin were 99.7%(n=9),100.2%(n=9),other tests accord with the standard of suppository. CONCLUSIONThe preparation of the Hollow Suppository is simple. And its quality can be well controlled.