Effects of Bastard Speedwell Total Flavonoids on Pathomorphology of Prostate and the Correlated Tissues of Prostatitis Model Mice

OBJECTIVE To investigate the effects of bastard speedwell total flavonoids decotion on pathomorphological changes of prostate, testicle and epididymis of prostatitis model mice.METHODS Sixty mice were randomly divided into 6 groups: normal group, prostatitis model group, QIANLIE KANG intervention group and high/middle/low dosage bastard speedwell total flavonoids intervention groups. The mouse prostatitis model was established by injecting 25% hemorrhoid injection into mouse prostate. On 21th day after drug intervention, the changes of prostate, testicle and epididymis histomorphology were observed by light microscope.RESULTS The pathomorphological changes of prostate,testicle and epididymis were slighter in bastard speedwell total flavonoids intervention groups than that of prostatitis model group, especially in the high/middle dosage groups, while the significant pathomorphological changes occurred in prostatitis model group. CONCLUSION Bastard speedwell total flavonoids may significantly relieve pathomorphological changes of prostate and testicle and epididymis.