The Clinical Report of 3 Cases of Antiepileptic Drug Hypersensitive Syndrome of Children

OBJECTIVE To investigate the clinical characteristics of antiepileptic drug hypersensitive syndrome (AHS) of children.METHODS To report 3 cases of AHS and review literature.RESULTS AHS is characterized by fever, skin rashes and involvement of the internal organs. Stevens-Johson syndrome (SJS) and toxic epidermal necrolysis (TEN) were observed in some patients. CONCLUSION It is important to make a correct diagnosis，stop hypersensitive antiepileptic drugs，and give treatment with corticosteroids and intravenous immune globulin.