Study on Ultra Sonic-assisted Total Coumarins Extraction from Angelica polymorpha Maxim.

OBJECTIVE To optimize ultra sonic-assisted extraction process of total coumarins from Angelica polymorpha Maxim.METHODS The extraction rate of total coumarins was used as index and the experimental conditions were investigated, such as solvent, extraction temperature, extration power, extration time, the ratio of solid to liquid and extraction times. The optimal extraction condition was obtained by orthogonal test.RESULTS Optimum technological conditions were determined as follows: 65 ℃, 90 W, 50 min, the ratio of solid to liquid was 1∶18,ultra sonic-assisted extracting for four times.CONCLUSION The process is feasible and useful for extracting total coumarins from Angelica polymorpha Maxim., with average extraction rate of total coumarins as 27.4 mg·g-1.