ZHANG Shan-tang, QU Jian, YANG Lin-hai, TANG Li-qin, WANG Ning-ling. Pharmacokinetics of High-Dose Methotrexate Infusion in Children with Acute Lymphoblastic Leukemia[J]. Chinese Journal of Modern Applied Pharmacy, 2008, (5): 454-458.
    Citation: ZHANG Shan-tang, QU Jian, YANG Lin-hai, TANG Li-qin, WANG Ning-ling. Pharmacokinetics of High-Dose Methotrexate Infusion in Children with Acute Lymphoblastic Leukemia[J]. Chinese Journal of Modern Applied Pharmacy, 2008, (5): 454-458.

    Pharmacokinetics of High-Dose Methotrexate Infusion in Children with Acute Lymphoblastic Leukemia

    • OBJECTIVE To evaluate the pharmacokinetics of methotrexate(MTX)in children with acute lymphoblastic leukemia(ALL)treated with high-dosage infusion of MTX and combination with calcium folinate(CF)rescued.METHODS The serum samples were collected at differen
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