Synthesis of Bis (S)-Naproxen Methyl Ester

XIE Yan-li, HU Ai-xi. Synthesis of Bis (S)-Naproxen Methyl Ester[J]. Chinese Journal of Modern Applied Pharmacy, 2007, (2): 127-129.

Citation:

XIE Yan-li, HU Ai-xi. Synthesis of Bis (S)-Naproxen Methyl Ester[J]. Chinese Journal of Modern Applied Pharmacy, 2007, (2): 127-129.

Citation:

XIE Yan-li, HU Ai-xi. Synthesis of Bis (S)-Naproxen Methyl Ester[J]. Chinese Journal of Modern Applied Pharmacy, 2007, (2): 127-129.

Abstract

OBJECTIVE Bis(S)-Naproxen methyl ester was designed and synthesized.METHODS The target compound was synthesized by the reaction of(S)-naproxen with chloromethyl ester of naproxen in the presence of K2CO3.The chloromethyl ester of naproxen was synthesized

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