WANG Mian, ZHANG Li-hui, ZHAO Zhan-sheng, DENG Yong-gui, ZHOU Hong, HAO Yong-mei, SHU Sheng-ou, CUI Wei. The Changes of Collagen Metabolism in Rat Heart with Type 2 Diabetes and Preventive Effect of Rosiglitazone[J]. Chinese Journal of Modern Applied Pharmacy, 2007, (2): 100-103.
    Citation: WANG Mian, ZHANG Li-hui, ZHAO Zhan-sheng, DENG Yong-gui, ZHOU Hong, HAO Yong-mei, SHU Sheng-ou, CUI Wei. The Changes of Collagen Metabolism in Rat Heart with Type 2 Diabetes and Preventive Effect of Rosiglitazone[J]. Chinese Journal of Modern Applied Pharmacy, 2007, (2): 100-103.

    The Changes of Collagen Metabolism in Rat Heart with Type 2 Diabetes and Preventive Effect of Rosiglitazone

    • OBJECTIVE To Investigate the changes of collagen accumulation,the MMP-2,MMP-9 and TIMP-1 mRNA expressions in cardiac tissue of the rat with type 2 diabetes at different stages and the role of rosiglitazone.METHODS The experimental type 2 diabetic rats wer
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