YAO Yan, HE Wen, ZHANG Mian, WANG Jun. Study on the penetration effect of N-trimethyl chitosan on Cyclosporin[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (9): 901-903.
    Citation: YAO Yan, HE Wen, ZHANG Mian, WANG Jun. Study on the penetration effect of N-trimethyl chitosan on Cyclosporin[J]. Chinese Journal of Modern Applied Pharmacy, 2006, (9): 901-903.

    Study on the penetration effect of N-trimethyl chitosan on Cyclosporin

    • OBJECTIVE To study the penetration effect of N-trimethyl chitosan(TMC) on Cyclosporin.METHODS TMC60 was synthesized by a two-step method using chitosan and methyl-iodide.The degree of quaternization(DQ) of TMC was determined by 1H-NMR.The excised mice ski
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